Genoa vs. Empoli: Predictions , Preview, Lineups, H2h for September 25, 2025

On September 25, 2025, Genoa will face Empoli in the Coppa Italia round of 32, with the match starting at 18:30 Central European Time. Here’s what you need to know.

Genoa

Genoa enters this cup match without a win in their last four games. The season began poorly: despite a 3-0 win against Vicenza Virtus in the Coppa Italia, they haven’t won in Serie A, with two draws and two losses. Their latest league match ended in a 1-2 loss at Bologna. At home, they have struggled, drawing 0-0 with Lecce and losing 0-1 to Juventus.

Last season, Genoa exited the Coppa Italia at this round, losing to Sampdoria. However, they have been consistent at home against Empoli, remaining unbeaten in their last eight home matches, with three wins and five draws.

Empoli

Empoli is playing in Serie B this season after being relegated. Last season’s highlight was reaching the Coppa Italia semi-finals, where they lost 1-2 to Bologna. This season has been rocky: in the Coppa Italia, they drew with Reggiana but advanced through penalties. In the league, they have one win in four matches but lost their last three, including a painful 0-4 defeat against Pescara.

Empoli has found it hard against Genoa, not winning any of their last 11 encounters since 2015.

Probable lineups

• Genoa: Leali, Martin, Vasquez, Norton-Cuffy, Marcandalli, Frendrup, Masini, Vitinha, Malinovskyi, Ellertsson, Colombo.
• Empoli: Furlan, Carboni, Lovato, Curto, Elia, Ebuehi, Gion, Siseau, Inyakkiti, Popov, Shpendi.

Key facts and head-to-head stats

• Genoa has not won 6 of their last 7 matches.
• Three of Genoa’s last four matches featured under 2.5 goals.
• Empoli have not won 8 of their last 9 matches.
• Empoli lost 5 of their last 6 away games.
• Genoa is unbeaten in their last 10 matches against Empoli.
• Four of the last five encounters had under 2.5 goals.
• Both teams scored in 6 of their last 8 matchups.

Genoa vs Empoli match prediction

Both teams are struggling to find form, but Genoa has a strong record against Empoli. They will be eager to secure their first home win of the season. Expect Genoa to perform well in this match. My prediction: Genoa to win at odds of 1.53.