Manchester United vs Chelsea: Prediction , Preview, Lineups, H2h for September 20, 2025

This Saturday at Old Trafford in Manchester, Manchester United will face Chelsea in one of the key fixtures of Premier League Matchday 5. Let’s look at the best betting option for this match, which has promising odds.

Match preview

Manchester United, currently under Ruben Amorim, are still trying to find their footing this season. They have had a shaky start, and their recent derby defeat against Manchester City was another setback. The team’s defense is weak, the attack lacks creativity, and injuries have highlighted the squad’s limited depth.

Home advantage at Old Trafford has diminished, with only 4 wins in their last 14 matches there. The issues extend beyond tactics, as the team struggles with pressure even at home. Facing a solid Chelsea, United has few clear strengths to rely on.

On the other hand, Chelsea have begun their season positively under Enzo Maresca. The team is structured well, efficient in scoring, and solid defensively. They are unbeaten in their last six matches, a reflection of a team that has found its identity.

Chelsea’s away performance is impressive as well, with just one defeat in their last 13 Premier League away games. Despite a busy schedule and some injuries, they have remained consistent. Expect Chelsea to employ a smart strategy to take advantage of United’s weaknesses.

Probable line-ups

• Manchester United: Bayindir, Yoro, de Ligt, Shaw, Mazraoui, Dorgu, Fernandes, Ugarte, Mbeumo, Diallo, Sesko
• Chelsea: Sanchez, Fofana, Chalobah, Adarabioyo, Hato, Caicedo, Fernandez, Buonanotte, Neto, Joao Pedro, Bynoe-Gittens

Match facts & head-to-head

• Chelsea are unbeaten in their last 6 Premier League matches — 4 wins and 2 draws.
• In their last 3 league encounters, Chelsea have won twice and drawn once.
• Manchester United have won only 4 of their last 14 home Premier League matches.

Prediction

Chelsea currently appear to be the more stable and confident team. They have not lost this season, while Manchester United is dealing with significant issues. Considering both teams’ recent performances, the best bet is on “Chelsea to win with a (0) handicap” at odds of 1.84.