Preview Preview, Lineups, H2h for Manchester City vs Manchester United – September 14, 2025

In the key match of Premier League Matchday 4, Manchester City will face Manchester United on Sunday, 14 September. The match will begin at 17:30 Central European Time. Here’s a betting tip for this crucial game.

See also: Burnley vs Liverpool prediction and betting tips 14 September 2025

Match preview

Manchester City has had a slow start to the season, managing just one win from their first three matches. After defeating Wolverhampton, City lost to Tottenham and Brighton, earning only three points and sitting in 13th place.

The team’s struggles began in the summer after their exit from the Club World Cup in the round of 16 against Saudi Arabia’s Al Hilal. As they head into the derby against Manchester United, City is not at their best.
Additionally, striker Omar Marmoush is injured from international duty with Egypt and will miss part of the season.

On the other hand, Manchester United has also had a difficult start. Under Ruben Amorim’s leadership, the Red Devils have secured one victory, following a win against Burnley. Prior to that, they lost to Arsenal and drew with Fulham.

United’s League Cup journey ended in disappointment as they were eliminated on penalties by League Two side Grimsby. This has been a challenging start for both Manchester clubs, making the derby a potential turning point or further complicating one team’s situation.

Probable line-ups

Manchester City: Donnarumma – Nunez, Dias, Gvardiol, Nouri – Rodri, Silva, Reijnders – Bobb, Doku – Haaland

Manchester United: Bayindir – Yoro, De Ligt, Shaw – Diallo, Casemiro, Mainoo, Dorgu – Mbeumo, Fernandes – Sesko

Match facts and head-to-head

• Manchester United has conceded in four consecutive matches
• The Over 2.5 goals bet has been successful in five of Manchester City’s last six games
• In their last ten meetings, City has won 5 times, United has 3 wins, and 2 matches have ended in draws

Prediction

I expect a high-scoring match as both teams are eager to improve, with defensive weaknesses likely amplifying the action. The best bet is on over 2.5 goals at odds of 1.58.