SSC Napoli vs Genoa: Predictions , Preview, Lineups, H2h for October 5, 2025

This Sunday, Serie A’s Matchday 6 features an important match at the Diego Armando Maradona Stadium in Naples, where Napoli will face Genoa. There’s a strong possibility of plenty of goals in this match.

Match Preview

Antonio Conte’s team recently faced their first league defeat in a while, losing to Milan and ending a 16-match unbeaten run. Despite this, Napoli remains a strong team at home, winning both of their home games so far this season.

However, Napoli’s defense has shown some weaknesses, conceding two goals in each of their last two matches. This might be a concern for Conte, as a solid defense is crucial for any title challenge. On the plus side, Napoli’s offense is still potent, and they usually manage to score at home.

Genoa has struggled at the start of the season, going five matches without a win, which keeps them near the bottom of the league. Their latest loss to Lazio (0-3) highlighted their difficulties and the gap in quality between teams.

On the road, Genoa has shown some ability, scoring seven goals in their last four away matches. However, they have struggled defensively, managing just one clean sheet in their last 12 away games, indicating issues in their defense.

Probable Line-ups

• Napoli: Vanja Milinković-Savić, Miguel Gutiérrez, Juan Jesus, Sam Beukema, Leonardo Spinazzola, Kevin De Bruyne, Stanislav Lobotka, André-Frank Zambo Anguissa, Scott McTominay, Rasmus Højlund, Matteo Politano.
• Genoa: Nicola Leali, Brooke Norton-Cuffy, Leo Østigård, Johan Vásquez, Aarón Martín Caricol, Vitinha, Morten Frendrup, Ruslan Malinovskyi, Patrizio Masini, Mikael Ellertsson, Lorenzo Colombo.

Match Facts and Head-to-Head

• Napoli has won 7 of their last 8 home matches in Serie A.
• Genoa has not won 12 of their last 13 away league games.
• In 9 of Napoli’s last 12 home games, 2 or 3 goals have been scored.

Prediction

Napoli is favored at home and is not expected to drop points after their recent loss to Milan. While Genoa may manage to score, their defense will likely struggle against Napoli’s attack. We recommend betting on over 2.0 total goals at odds of 1.67.